Hair Loss

Hair loss due to male pattern baldness occurs when DHT, a male androgen hormone, begins to affect the integrity of hair follicles and interrupts the hair growth cycle. Additional evidence of the efficacy of finasteride in the treatment of MAA is observed in a randomized, double-blind, placebo-controlled, double study . At month 12, all subjects in the finasteride group showed an increase in hair count, while a decrease was found in 44% of the placebo group. Serum DHT levels decreased significantly in the finasteride group, with no significant change observed in the placebo group.

Testosterone plays a key role in the baldness of the male pattern, but it only affects hair follicle cells that are genetically susceptible to the condition. In sensitive men, testosterone comes into contact with an enzyme that occurs in the hair follicles. When this happens, testosterone is converted into dihydrotestosterone, a more powerful androgen that can bind to receptors in follicles, Dr. Richard A. Strick, dermatologist at the University of California, Los Angeles. This binding, in turn, can cause a change in the genetic activity of cells, initiating the gradual process of hair loss. Both men and women can lose hair for various reasons, including poor nutrition, thyroid disease, hormonal fluctuations, genetics and age. But by far the most common type of hair loss is what affects many men in the prime of their lives.

Bald patients often describe periods of excessive hair disclosure, most notably when combing or washing. This is due to the relative increase in the number of follicles in telogen. Because the hair growth rate remains relatively constant, the duration of the anagenic growth determines the 防脫髮洗頭水 length of the hair. Therefore, the length of each hair strain is reduced with each successively shortened hair cycle. Ultimately, the duration of the anagen becomes so short that the growing hair does not grow long enough to reach the skin surface, leaving an empty follicular pore behind.

The most common side effects are mild scalp irritation, allergic contact dermatitis and unwanted hair in other parts of the body. Treating pattern hair loss can simply mean that you accept the condition, which may also include shaving your head. Interventions that can be tried include minoxidil medications and hair transplantation. Alopecia areata can be treated with steroid injections into the affected area, but these must be repeated regularly to be effective.

Visit our FREE online webbook to fully cover this and all related areas of endocrinology Several studies have demonstrated the beneficial effects of finasteride in MAA, with the highest number of benefits observed in patients with mainly type III vertex or Hamilton / Norwood type IV hair loss (123,). Finasteride would slow MAA progression and cause partial growth in about two-thirds of men . A study of measuring hair counts with macro photos showed that the total number of hair and anagenic substances increases with the treatment of finasteride . A significant increase in the anagen / telogen ratio was also achieved.

A family tendency towards MAA and racial variation in prevalence is widely recognized and inheritance represents about 80% of the predisposition. Normal androgen levels are sufficient to cause hair loss in genetically sensitive individuals. A person’s genetic makeup, along with external factors such as stress, can also lead to hair loss.